Basim. M. Ayesh

I hold a bachelor's degree in biology and biochemistry from Birzeit University in 1997 and a master's and doctorate from the Department of Molecular Biochemistry at the Hebrew University of Jerusalem in 2004.

The doctoral thesis dealt with the design of a gene therapy for bladder cancer that works on the release of diphtheria toxin in cancer cells under the control of IGFII promoter.
This treatment has been tested in cancer cells cultured in the laboratory as well as in a number of animal models for bladder cancer in mice and rats. These studies have been successful.
After graduation I worked in the Central Laboratory of the Palestinian Ministry of Health as a molecular genetics specialist. I established and operated the first molecular genetics laboratory concerned with the Molecular diagnosis of various viral and bacterial diseases. At the same time, I began working on the graduate program in Life Sciences at the Islamic University where I taught courses in Molecular Cell Biology, Advanced Biochemistry and Enzymes and Hormones. I have also supervised on more than 20 master's thesis and discussed a number of others at the Islamic University.
In 2009 I moved from the Ministry of Health to work as an assistant professor at Al-Aqsa University and helped establish and operate the Department of Laboratory Medical Sciences in which I now work as an associate professor in molecular genetics. In the same year I started teaching genetics and molecular biology courses for medical students at the Islamic University until the moment.
My research interests, which focused on molecular genetics and molecular diagnostics, have led to the publication of more than 30 scholarly articles in prestigious international, regional and local journals, as well as the publication of a chapter in Springer's book.

Research interests

Who am I?

About Me



I am a Palestinian academic born in Gaza and a distinguished researcher in applied mathematics, obtained a professorship in mathematics and mathematical physics.

Date & Place of Birth December 02, 1970
Residence Palestine
Phone 00970-8-2641622



Courses taught




Scientific Research

Cited by
Fecal carriage of extended-spectrum β-lactamase-producing enterobacterales from hospitals and community settings in Gaza Strip, Palestine
NA El Aila, NAA Laham, BM Ayesh, T Naas
BMC microbiology 23 (1), 376, 2023
Prevalence of extended spectrum beta lactamase and molecular detection of blaTEM, blaSHV and blaCTX-M genotypes among Gram negative bacilli isolates from pediatric patient …
NA El Aila, NA Al Laham, BM Ayesh
BMC Infectious Diseases 23 (1), 99, 2023
Alpha-mangostin attenuates the apoptotic pathway of abamectin in the fetal rats’ brain by targeting pro-oxidant stimulus, catecholaminergic neurotransmitters, and …
KA Ibrahim, M Eleyan, SA Khwanes, RA Mohamed, BM Ayesh
Drug and chemical toxicology 45 (6), 2496-2508, 2022
MicroRNA-targeting in male infertility: Sperm microRNA-19a/b-3p and its spermatogenesis related transcripts content in men with oligoasthenozoospermia
M Abu-Halima, LS Becker, BM Ayesh, E Meese
Frontiers in Cell and Developmental Biology 10, 973849, 2022
Antibiotic resistant and mecA gene characterization of Staphylococcus epidermidis isolated from five hospitals in Gaza strip
MAAF Alnajar, SM Abdelsalam, NA El Aila, BM Ayesh, MI Fahd
Journal of Scientific Research in Science, 2022
MicroRNA‐targeting in spermatogenesis: Over‐expressions of microRNA‐23a/b‐3p and its affected targeting of the genes ODF2 and UBQLN3 in spermatozoa of …
M Abu‐Halima, A Belkacemi, BM Ayesh, L Simone Becker, AM Sindiani, ...
Andrology 9 (4), 1137-1144, 2021
Characterization of micro-RNA in women with different ovarian reserve
M Abu-Halima, LS Becker, BM Ayesh, SL Baus, A Hamza, U Fischer, ...
Scientific Reports 11 (1), 13351, 2021
Integrated microRNA and mRNA expression profiling identifies novel targets and networks associated with Ebstein’s anomaly
M Abu-Halima, V Wagner, LS Becker, BM Ayesh, M Abd El-Rahman, ...
Cells 10 (5), 1066, 2021
MicroRNA-targeting in spermatogenesis: Over-expressions of microRNA-23a/b-3p and its affected targeting of the genes ODF2 and UBQLN3 in sperm of patients with …
M Abu-Halima, B Ayesh, L Becker, M Hammadeh, A Keller, M Eckart
HUMAN REPRODUCTION 35, 110-110, 2020
Antibiotic resistance and mecA gene characterization of Staphylococcus epidermidis isolated from some hospitals in Gaza strip
MAA Alnajar, SM Abdelsalam, NA El Aila, BM Ayesh, MI Fahd
Journal of Scientific Research in Science 37 (Part 2 (Biological Sciences …, 2020
MicroRNAs in combined spent culture media and sperm are associated with embryo quality and pregnancy outcome
M Abu-Halima, ZA Khaizaran, BM Ayesh, U Fischer, SA Khaizaran, ...
Fertility and sterility 113 (5), 970-980. e2, 2020
Differential expression of miR-23a/b-3p and its target genes in male patients with subfertility
M Abu-Halima, BM Ayesh, M Hart, J Alles, U Fischer, M Hammadeh, ...
Fertility and Sterility 112 (2), 323-335. e2, 2019
Gene therapy of bladder cancer and colorectal metastasis in the liver: Isulin like growth factor 2 P3 and P4 regulatory sequences controlled suicidal therapy of cancer cells
B Ayesh
VDM Verlag, 2019
The clinical effects of CYP2C19 *2 allele frequency on Palestinian patients receiving clopidogrel after percutaneous coronary intervention
BM Ayesh, IR Al-Astal, MM Yassin
International journal of clinical pharmacy 41 (1), 96-103, 2019
Overexpression of TBX3 transcription factor as a potential diagnostic marker for breast cancer
S Aliwaini, AM Lubbad, A Shourfa, HAA Hamada, B Ayesh, ...
Molecular and clinical oncology 10 (1), 105-112, 2019
CHRNA5 and CHRNA3 polymorphism and lung cancer susceptibility in Palestinian population
BM Ayesh, R Al-Masri, AA Abed
BMC research notes 11, 1-6, 2018
يناثلا عونلا نم ةزغ عاطق يف
NMA Qaddoura, S Aliwaini, B Ayesh
Evaluation of CYP2C9- and VKORC1-based pharmacogenetic algorithm for warfarin dose in Gaza-Palestine
BM Ayesh, AS Abu Shaaban, AA Abed
Future science OA 4 (3), FSO276, 2018
HLA-DQ2 and-DQ8 haplotypes frequency and diagnostic utility in celiac disease patients of Gaza strip, Palestine
BM Ayesh, EK Zaqout, MM Yassin
Autoimmunity Highlights 8, 1-6, 2017
Nasal carriage of methicillin resistant Staphylococcus aureus among health care workers at Al Shifa hospital in Gaza Strip
NA El Aila, NA Al Laham, BM Ayesh
BMC infectious diseases 17, 1-7, 2017
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Year : 2004The Hebrew University of Jerusalem ,

Year : 2000The Hebrew University of Jerusalem ,



General Biology Laboratory 1

Diagnostic Molecular Biology



Medical Terminology


Cancer Biology

Molecular Biology

Cell Biology

Medical Genetics

Basics of Molecular Medicine

General Biology 1


09/08/2022 -


18/09/2017 - - 23/03/2022

Assistant Vice President for Academic Affairs

17/01/2011 - - 22/01/2012

Head of Biology

17/01/2011 - - 01/11/2011

Head of Medical Technology